Adults 65 years and older may qualify for a study evaluating an investigational vaccine designed to help prevent C. difficile (C. diff) infection.
C. diff Prevention
Age Range:
65
Gender:
Male and Female
Location:
Rochester, New York
About the Study
Researchers are working to develop vaccines that may help prevent C. diff infections before they occur. This study is evaluating an investigational vaccine to better understand its safety, tolerability, and how well it may help protect against C. diff infection.
Participants in this study will receive either the investigational C. diff vaccine or a placebo (an inactive substance that looks like the vaccine but does not contain active ingredients). There is a 50% chance of receiving placebo.
Qualifications
You may be able to join if you:
- Are 65 years of age or older.
- Do not have a history of C. diff infection.
- Have at least one risk factor for C. diff infection, such as recent hospitalization, frequent healthcare visits, or recent antibiotic use.
- Are not currently experiencing frequent diarrhea or active gastrointestinal conditions.
- Do not have certain medical conditions that may affect participation, such as severe immunodeficiency or unstable health conditions.
- At least 1 inpatient hospitalization for >2 nights duration in the past year, or at least 2 emergency room visits in the past year
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